One of the most sought-after comedians, Amy Sedaris, has inked a deal with 20th Century Fox TV to create, write and star in a comedy series project. Sedaris will pen the script with her writing partner Paul Dinello, who also is attached to direct. The single-camera project will be co-produced by David Letterman’s Worldwide Pants, which has a first-look deal with Sedaris, a longtime friend of Letterman’s and a frequent guest on his “Late Show” on CBS. Sedaris and Dinello are “fleshing out” the premise for the show, which is based on an idea Sedaris came up with about six years ago. “It just seemed the right time to do it now,” she said. Busy filming an arc on TNT’s “The Closer” as the sister of agent Fritz Howard (Jon Tenney) and promoting the paperback release of her book “I Like You,” Sedaris said she wasn’t looking to do a series and almost didn’t take the meeting with 20th TV’s head of comedy Jonathan Davis. But “we just hit it off,” Sedaris said. While the show will be scripted, there will be room for Second City alumna to showcase her improv skills. The project will be taken out to the networks in the next few weeks, with Sedaris and Dinello hoping it will land on cable.